Baseline and Impact of First-Year Intervention on Schistosoma haematobium Infection in Seasonal Transmission Foci in the Northern and Central Parts of Côte d’Ivoire

In order to assess the impact of different control strategies against Schistosoma haematobium in seasonal transmission foci Côte d’Ivoire, a three-year cluster randomized trial was implemented. The decrease S. prevalence among children aged 9−12 years primary outcome. first step, an eligibility survey conducted, subjecting 50 13−14 single urine filtration. Sixty-four villages with ≥4% were selected and randomly assigned four intervention arms consisting annual mass drug administration (MDA) before (arm 1) after 2) peak transmission, biannual treatment praziquantel season 3), MDA season, coupled focal chemical snail using molluscicides 4). At baseline, we observed 24.8%, 10.1%, 13.9%, 15.9% study 1, 2, 3, 4, respectively. One year intervention, decreased all by about two-thirds or more. arm 2 lower than 1 (3.5% vs. 8.1%), but difference not statistically significant (odds ratio (OR) = 0.42, 95% confidence interval (CI) 0.10−1.80). After adjusting for baseline prevalence, performed roughly similarly (adjusted odds (aOR) 1.03, CI 0.34−3.07). 3 4 (1.9% 2.2%) significantly compared unadjusted adjusted models OR 0.22, 0.05−0.95, aOR 0.19, 0.08−0.48; 0.26, 0.08−0.85, 0.23, 0.06−0.87). initial showed on haematobium. It will be interesting monitor comparative determine whether interruption can achieved this epidemiological setting within three years.